Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of the UVA induction of haem oxygenase‐1 expression by β‐carotene in human skin fibroblasts

25 Oct 1999

Abstract excerpt

beta-Carotene has often been discussed as a means to reduce the risk of skin photodamage. We studied the antioxidative potential of beta-carotene in human skin fibroblasts exposed to ultraviolet A light. Surprisingly, we found a pro-oxidative effect of beta-carotene. Using the induction of haem oxygenase-1 as a marker for oxidative stress, we found a strong enhancement of gene expression by beta-carotene in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidant Activity and Oxidative Stress
Share to Free Radicals and Antioxidants
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10544237
DOI: 10.1016/s0014-5793(99)01342-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Enhancement of the UVA induction of haem oxygenase‐1 expression by β‐carotene in human skin fibroblastsPMID 10544237Read ↗

A broad-spectrum sunscreen prevents UVA radiation-induced gene expression in reconstructed skin in vitro and in human skin in vivoSemantic proximity Read ↗

Solar Ultraviolet A Radiation: An Oxidizing Skin Carcinogen that Activates Heme Oxygenase-1Semantic proximity Read ↗

TWO GENES CONTRIBUTE TO DIFFERENT EXTENTS TO THE HEME OXYGENASE ENZYME ACTIVITY MEASURED IN CULTURED HUMAN SKIN FIBROBLASTS AND KERATINOCYTES: IMPLICATIONS FOR PROTECTION AGAINST OXIDANT STRESSSemantic proximity Read ↗

Effect of antioxidant supplementation on the adaptive response of human skin fibroblasts to UV-induced oxidative stressSemantic proximity Read ↗

Beta-carotene suppresses UVA-induced HO-1 gene expression in cultured FEK4Semantic proximity Read ↗

Ultraviolet Radiation-Induced Production of Nitric Oxide:A multi-cell and multi-donor analysisSemantic proximity Read ↗

Increase of CYP1B1 Transcription in Human Keratinocytes and HaCaT Cells after UV-B ExposureSemantic proximity Read ↗

Protective effects of antioxidants against UVA-induced DNA damage in human skin fibroblasts in cultureSemantic proximity Read ↗

Ascorbic acid and beta-carotene as modulators of oxidative damageSemantic proximity Read ↗

UV-A-induced AP-1 activation requires the Raf/ERK pathway in human NCTC 2544 keratinocytes.Semantic proximity Read ↗

<i>In vivo</i>Raman spectroscopy detects increased epidermal antioxidative potential with topically applied carotenoidsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.