Article
Etiology of fibrous dysplasia and McCune-Albright syndrome.
International journal of oral and maxillofacial surgery - 1 Oct 1999
Cohen M M, Howell R E
Abstract excerpt
In this paper, the etiology of monostotic fibrous dysplasia and McCune-Albright syndrome is explained. Both monostotic fibrous dysplasia and McCune-Albright syndrome are sporadically occurring disorders in which a mutation in the GNAS1 gene occurs postzygotically in a somatic cell. All cells descended from the mutated cell can manifest features of McCune-Albright syndrome or fibrous dysplasia. Cells descended...
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