Article
The T102C polymorphism of the 5-HT2A-receptor gene in fibromyalgia.
Neurobiology of disease - 1 Oct 1999
Bondy B, Spaeth M, Offenbaecher M, Glatzeder K, Stratz T, Schwarz M, de Jonge S, Krüger M, Engel R R, Färber L, Pongratz D E, Ackenheil M
Abstract excerpt
Based on a possible involvement of serotonergic dysfunction in the pathophysiology of fibromyalgia (FM) and on preliminary reports of a possible genetically driven vulnerability for this disorder we investigated the silent T102C polymorphism of the 5-HT2A-receptor gene in 168 FM patients and 115 healthy controls. Our results showed a significantly different genotype distribution in FM patients with a decrease in...
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