Article
Quorum sensing-dependent regulation and blockade of exoprotease production in Aeromonas hydrophila.
Infection and immunity - 1 Oct 1999
Swift S, Lynch M J, Fish L, Kirke D F, Tomás J M, Stewart G S, Williams P
Abstract excerpt
In Aeromonas hydrophila, the ahyI gene encodes a protein responsible for the synthesis of the quorum sensing signal N-butanoyl-L-homoserine lactone (C4-HSL). Inactivation of the ahyI gene on the A. hydrophila chromosome abolishes C4-HSL production. The exoprotease activity of A. hydrophila consists of both serine protease and metalloprotease activities; in the ahyI-negative strain, both are substantially reduced...
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