Article
Methylenetetrahydrofolate reductase (MTHFR): the incidence of mutations C677T and A1298C in the Ashkenazi Jewish population.
American journal of medical genetics - 8 Oct 1999
Rady P L, Tyring S K, Hudnall S D, Vargas T, Kellner L H, Nitowsky H, Matalon R K
Abstract excerpt
The polymorphic mutation C677T in the gene of MTHFR is considered a risk mutation for spina bifida and vascular disease. Another common mutation on the MTHFR gene, A1298C, has also been described as another risk mutation. We studied the frequencies of these two mutations on DNA samples from healthy Jewish individuals and compared them to the frequency of these mutations in DNA samples obtained from healthy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.