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Article

Linkage analysis of the hph-1 mutation and the GTP cyclohydrolase I structural gene.

Molecular genetics and metabolism - 1 Sept 1999

Montañez C S, McDonald J D

Abstract excerpt

Our research establishes genetic linkage between the hph-1 mutation and the GTP-CH I structural gene. Our results indicate that these two loci are within an 8 cM region with 95% confidence. This finding lends additional support for the use of the hph-1 mouse mutant as a bona fide model system for the human disorder GTP-CH I to further our understanding of the molecular mechanisms involved in the disease pathology...

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Identifiers

PMID: 10479487
DOI: 10.1006/mgme.1999.2887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Linkage analysis of the hph-1 mutation and the GTP cyclohydrolase I structural gene.PMID 10479487Read ↗

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