Genetic mapping of hph2, a mutation affecting amino acid transport in the mouse.

doi:10.1007/s003359900366

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Article

Genetic mapping of hph2, a mutation affecting amino acid transport in the mouse.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 1997

Symula D J, Shedlovsky A, Dove W F

Abstract excerpt

We describe the genetic mapping of hyperphenylal-aninemia 2 (hph2), a recessive mutation in the mouse that causes deficient amino acid transport similar to Hartnup disorder, a human genetic amino acid transport disorder. The hph2 locus was mapped in three separate crosses to identify candidate ge...

Topics

Animals
Biological Transport
Chromosome Mapping
Crosses, Genetic
Disease Models, Animal
Hartnup Disease
Humans
Mice
Mice, Inbred C57BL
Mutation
Phenylalanine

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