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Article

French Machado-Joseph disease patients do not exhibit gametic segregation distortion: a sperm typing analysis.

Human molecular genetics - 1 Sept 1999

Grewal R P, Cancel G, Leeflang E P, Dürr A, McPeek M S, Draghinas D, Yao X, Stevanin G, Alnot M O, Brice A, Arnheim N

Abstract excerpt

Segregation distortion has been reported to occur in a number of the trinucleotide repeat disorders. On the basis of a sperm typing study performed in patients of Japanese descent with Machado-Joseph disease (MJD), it was reported that disease alleles are preferentially transmitted during meiosis. We performed a sperm typing study of five MJD patients of French descent and analysis of the pooled data shows a...

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PMID: 10441343
DOI: 10.1093/hmg/8.9.1779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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French Machado-Joseph disease patients do not exhibit gametic segregation distortion: a sperm typing analysis.PMID 10441343Read ↗

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