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Article

A mouse gene knockout model for juvenile ceroid-lipofuscinosis (Batten disease).

Journal of neuroscience research - 15 Aug 1999

Katz M L, Shibuya H, Liu P C, Kaur S, Gao C L, Johnson G S

Abstract excerpt

The human hereditary ceroid-lipofuscinoses are a group of autosomal recessively inherited diseases characterized by massive accumulations of autofluorescent lysosomal storage bodies in the cells of many tissues and by neuronal degeneration throughout the central nervous system. There are a number...

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Source

Identifiers

PMID: 10440905

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10440905-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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A mouse gene knockout model for juvenile ceroid-lipofuscinosis (Batten disease).PMID 10440905Read ↗

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Current Insights in Elucidation of Possible Molecular Mechanisms of the Juvenile Form of Batten Disease.Semantic proximity Read ↗

Deletion of the Caenorhabditis elegans homologues of the CLN3 gene, involved in human juvenile neuronal ceroid lipofuscinosis, causes a mild progeric phenotype.Semantic proximity Read ↗

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