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Article

Nijmegen breakage syndrome: consequences of defective DNA double strand break repair.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Aug 1999

Digweed M, Reis A, Sperling K

Abstract excerpt

The autosomal recessive genetic disorder, Nijmegen Breakage Syndrome, is characterised by an excessively high risk for the development of lymphatic tumours and an extreme sensitivity towards ionising radiation. The most likely explanation for these characteristics, a deficiency in the repair of D...

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Identifiers

PMID: 10440861
DOI: 10.1002/(SICI)1521-1878(199908)21:8<649::AID-BIES4>3.0.CO;2-O

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10440861-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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