Article
T cell numbers relate to bone involvement in Gaucher disease.
Blood cells, molecules & diseases - 1 Apr 1999
Lacerda L, Arosa F A, Lacerda R, Cabeda J, Porto G, Amaral O, Fortuna A, Pinto R, Oliveira P, McLaren C E, Sá Miranda C, de Sousa M
Abstract excerpt
The major elements of bone pathology in Gaucher disease are a failure of osteoclast and osteoblast function, resulting in osteopenia and also osteonecrosis. T lymphocytes have recently been found to be involved in the regulation of osteoblast/osteoclast activity in vitro. In the present report the peripheral blood T major lymphocyte subsets were investigated in a group of genotyped type 1 Gaucher disease...
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