Article
Efficacy of interferon treatment for patients with chronic hepatitis C: comparison of response in cirrhotics, fibrotics, or nonfibrotics.
Hepatology (Baltimore, Md.) - 1 Jul 1999
Everson G T, Jensen D M, Craig J R, van Leeuwen D J, Bain V G, Ehrinpreis M N, Albert D, Joh T, Witt K
Abstract excerpt
Chronic hepatitis C patients (472 patients) were treated with consensus interferon (CIFN) or interferon (IFN) alfa-2b for 6 months in a large multicenter trial. Efficacy was assessed by clearance of hepatitis C virus (HCV) RNA using reverse transcription polymerase chain reaction (RT-PCR) (<100 copies/mL), normalization of serum alanine aminotransferase (ALT), and histological improvement. The purpose of these...
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