Role of Hemolysin BL in the Pathogenesis of Extraintestinal <i>Bacillus cereus</i> Infection Assessed in an Endophthalmitis Model

Abstract excerpt

Bacillus cereus is a rare cause of serious human infection but, paradoxically, causes one of the most severe posttraumatic or endogenous infections of the eye, endophthalmitis, which frequently results in blindness. The virulence of B. cereus endophthalmitis historically has been attributed to toxin production. We therefore sought to examine the contribution of the dermonecrotic toxin, hemolysin BL, to the...

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