Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Carrier rates in the midwestern United States for GJB2 mutations causing inherited deafness.

JAMA - 16 Jun 1999

Green G E, Scott D A, McDonald J M, Woodworth G G, Sheffield V C, Smith R J

Abstract excerpt

CONTEXT: Mutations in the GJB2 gene are the most common known cause of inherited congenital severe-to-profound deafness. The carrier frequency of these mutations is not known. OBJECTIVES: To determine the carrier rate of deafness-causing mutations in GJB2 in the midwestern United States and the prevalence of these mutations in persons with congenital sensorineural hearing loss ranging in severity from moderate to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Connexin 26
Share to Connexins
Share to Deafness

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Recessive

Share to Hearing Loss, Sensorineural

Share to Midwestern United States

Share to Polymorphism, Single-Stranded Conformational

Share to Statistics as Topic

Source

Identifiers

PMID: 10376574
DOI: 10.1001/jama.281.23.2211

Genes

GJB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Carrier rates in the midwestern United States for GJB2 mutations causing inherited deafness.PMID 10376574Read ↗

Frequency of GJB2 mutations in patients with nonsyndromic hearing loss from an ethnically characterized Brazilian population.Semantic proximity Read ↗

Genetic testing for hereditary hearing loss: connexin 26 (GJB2) allele variants and two novel deafness-causing mutations (R32C and 645-648delTAGA).Semantic proximity Read ↗

Genotypic and phenotypic correlations of DFNB1-related hearing impairment in the Midwestern United States.Semantic proximity Read ↗

A genotype-phenotype correlation for GJB2 (connexin 26) deafness.Semantic proximity Read ↗

Molecular genetics of hearing impairment due to mutations in gap junction genes encoding beta connexins.Semantic proximity Read ↗

Frequency and distribution of GJB2 (connexin 26) and GJB6 (connexin 30) mutations in a large North American repository of deaf probands.Semantic proximity Read ↗

GJB2: the spectrum of deafness-causing allele variants and their phenotype.Semantic proximity Read ↗

GJB2 c.-23+1G>A mutation is second most common mutation among Iranian individuals with autosomal recessive hearing loss.Semantic proximity Read ↗

Prevalence of 35delG/GJB2 and del (GJB6-D13S1830) mutations in patients with non-syndromic deafness from a population of Espírito Santo-Brazil.Semantic proximity Read ↗

Prevalence of the 35delG mutation in the GJB2 gene in two samples of non-syndromic deaf subjects from Chile.Semantic proximity Read ↗

GJB2 sequencing in deaf and profound sensorineural hearing loss children.Semantic proximity Read ↗

Determination of the carrier frequencies of selected GJB2 mutations in the Korean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.