Article
The gene for cherubism maps to chromosome 4p16.
American journal of human genetics - 1 Jul 1999
Tiziani V, Reichenberger E, Buzzo C L, Niazi S, Fukai N, Stiller M, Peters H, Salzano F M, Raposo do Amaral C M, Olsen B R
Abstract excerpt
Cherubism is an autosomal dominant disorder that may be related to tooth development and eruption. It is a disorder of age-related bone remodeling, mostly limited to the maxilla and the mandible, with loss of bone in the jaws and its replacement with large amounts of fibrous tissue. We have used a genomewide search with a three-generation family and have established linkage to chromosome 4p16. Three other...
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