Article
Coronary heart disease. At the interface of molecular genetics and preventive medicine.
American journal of preventive medicine - 1 Feb 1999
Ellsworth D L, Sholinsky P, Jaquish C, Fabsitz R R, Manolio T A
Abstract excerpt
BACKGROUND: Susceptibility to common chronic diseases such as coronary heart disease (CHD) appears to be influenced by "context-dependent effects," which include interactions among genes (genetic epistasis) and among genes and environmental factors (gene-environment interactions). METHODS: A synthesis of current knowledge and research findings demonstrates the importance of integrating genetic research on...
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