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Article

Evaluation of Recombinant Antigens for Serodiagnosis of Chagas’ Disease in South and Central America

1 May 1999

Abstract excerpt

The commercially available diagnostic tests for Chagas' disease employ whole extracts or semipurified fractions of Trypanosoma cruzi epimastigotes. Considerable variation in the reproducibility and reliability of these tests has been reported by different research laboratories, mainly due to cross-reactivity with other pathogens and standardization of the reagents. The use of recombinant antigens for the...

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PMID: 10203520
DOI: 10.1128/jcm.37.5.1554-1560.1999

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