Article
Transmembrane Insertion of the<i>Toxoplasma gondii</i>GRA5 Protein Occurs after Soluble Secretion into the Host Cell
1 Apr 1999
Abstract excerpt
The intracellular parasite Toxoplasma gondii resides within a specialized compartment, the parasitophorous vacuole (PV), that resists fusion with host cell endocytic and lysosomal compartments. The PV is extensively modified by secretion of parasite proteins, including the dense granule protein GRA5 that is specifically targeted to the delimiting membrane of the PV (PVM). We show here that GRA5 is present both in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
