Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174.

Clinical pharmacology and therapeutics - 1 Mar 1999

McCrea J B, Cribb A, Rushmore T, Osborne B, Gillen L, Lo M W, Waldman S, Bjornsson T, Spielberg S, Goldberg M R

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Arrhythmia Agents
Share to Antihypertensive Agents
Share to Cytochrome P-450 CYP3A

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Imidazoles

Share to Losartan

Share to Steroid 16-alpha-Hydroxylase

Share to Steroid Hydroxylases

Share to Tetrazoles

Source

Identifiers

PMID: 10096267
DOI: 10.1016/S0009-9236(99)70114-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Phenotypic and genotypic investigations of a healthy volunteer deficient in the conversion of losartan to its active metabolite E-3174.PMID 10096267Read ↗

Impaired (S)-warfarin metabolism catalysed by the R144C allelic variant of CYP2C9.Semantic proximity Read ↗

Severely diminished response to vitamin K-treatment for self-inflicted warfarin intoxication in a patient genotyped as CYP2C9*3*3.Semantic proximity Read ↗

Detection of heterozygotes for recessive alleles. Homocyst(e)inemia: paradigm of pitfalls in phenotypes.Semantic proximity Read ↗

Losartan hydroxylation phenotype in an Ecuadorian population: influence of CYP2C9 genetic polymorphism, habits and gender.Semantic proximity Read ↗

Development of a HPLC method for the determination of losartan urinary metabolic ratio to be used for the determination of CYP2C9 hydroxylation phenotypes.Semantic proximity Read ↗

Human Metabolic Enzymes Deficiency: A Genetic Mutation Based ApproachSemantic proximity Read ↗

Human biochemical genetics: an insight into inborn errors of metabolism.Semantic proximity Read ↗

Genetics, diagnosis and treatment of hemochromatosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.