Article
Pentanucleotide repeat and size polymorphisms in the apolipoprotein(a) gene are associated with the lipoprotein(a) concentration in chronic hemodialysis patients.
Nephron - 1 Jan 1999
Tanaka M, Yanagi H, Ando R, Kurihara S, Hirano C, Kobayashi K, Kikuchi S, Hamaguchi H, Tsuchiya S, Tomura S
Abstract excerpt
The elevation of serum or plasma lipoprotein(a) [Lp(a)] levels is regarded as an independent risk factor for cardiovascular disease, and many previous reports demonstrated that Lp(a) levels in hemodialysis patients were significantly higher than in controls. The purpose of this study was to investigate the effect of a pentanucleotide repeat polymorphism [(TTTTA)n] in the 5'-flanking region of the...
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