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Article

Antigen-specific B-cell unresponsiveness induced by chronic Mycobacterium avium subsp. paratuberculosis infection of cattle.

Infection and immunity - 1 Apr 1999

Waters W R, Stabel J R, Sacco R E, Harp J A, Pesch B A, Wannemuehler M J

Abstract excerpt

Mycobacterium avium subsp. paratuberculosis infection of cattle results in a chronic granulomatous enteritis. Clinical disease (i.e., cachexia, diarrhea, and high fecal bacterial counts) is preceded by a lengthy subclinical stage of disease. The immunologic mechanisms associated with the progression of infected cattle from subclinical to clinical disease are unclear. In this study, a cell proliferation assay was...

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Source

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Identifiers

PMID: 10084991
DOI: 10.1128/IAI.67.4.1593-1598.1999
PMCID: PMC96501

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Source receipt: pubmed, retrieved 7 Sept 2026.

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