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Article

Identification of mutations in the <i>c-mpl</i> gene in congenital amegakaryocytic thrombocytopenia

16 Mar 1999

Abstract excerpt

Congenital amegakaryocytic thrombocytopenia (CAMT) is a rare disorder expressed in infancy and characterized by isolated thrombocytopenia and megakaryocytopenia with no physical anomalies. Our previous hematological analysis indicated similarities between human CAMT and murine c-mpl (thrombopoietin receptor) deficiency. Because the c-mpl gene was considered as one of the candidate genes for this disorder, we...

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PMID: 10077649
DOI: 10.1073/pnas.96.6.3132

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