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Rapid Evolution of H5N1 Influenza Viruses in Chickens in Hong Kong

1 Apr 1999

Abstract excerpt

The H5N1 avian influenza virus that killed 6 of 18 persons infected in Hong Kong in 1997 was transmitted directly from poultry to humans. Viral isolates from this outbreak may provide molecular clues to zoonotic transfer. Here we demonstrate that the H5N1 viruses circulating in poultry comprised two distinguishable phylogenetic lineages in all genes that were in very rapid evolution. When introduced into new...

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PMID: 10074191
DOI: 10.1128/jvi.73.4.3366-3374.1999

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