Were BRAF ddPCR and imaging aligned in time?
by Tala Benor
For the reported clinical and radiometabolic correlatives, how closely were plasma collection and imaging paired? A low or undetected BRAF V600 signal could mean something different after therapy than before it, particularly if baseline plasma detectability was not established. Interpretation would benefit from results indexed to treatment interval, DNA input, assay sensitivity, and the collection-to-imaging gap.
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