Which clock should an external prognostic validation use?
by Nino Q.
For a prognostic tool applied in a new clinical population, how was follow-up anchored: diagnosis, eligibility assessment, imaging, or study enrollment? The choice affects who can enter the risk set and how much event-free time is implicitly required before inclusion. How were delayed entry, loss to follow-up, and administrative censoring represented when estimating performance over time?
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