Article

Single-nucleus RNA-sequencing reveals novel potential mechanisms of ovarian insufficiency in 45,X Turner Syndrome

2023-12-23

Abstract excerpt

<h4>Study question</h4> Can single-nuclei and bulk RNA sequencing technologies be used to elucidate novel mechanisms of ovarian insufficiency in Turner Syndrome (TS)? <h4>Summary answer</h4> Using single-nucleus and bulk RNA sequencing approaches, we identified novel potential pathogenic mechanisms underlying ovarian insufficiency in TS including and beyond X chromosome haploinsufficiency. <h4>What is known alre...

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Literature Corpus work: dd1eaf01-f68a-5713-8452-291728edf25a
DOI: 10.1101/2023.12.22.572342

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