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Strain-specific anti-RBD IgG antibody titers against the WT, XBB.1.5, JN.1, and KP.3 strains consistently correlate with neutralizing activity following SARS-CoV-2 XBB.1.5-adapted mRNA vaccination

2025-03-14

Abstract excerpt

<h4>Introduction</h4> Data on the correlation between SARS-CoV-2 neutralizing activity and strain-specific anti-RBD IgG antibody (anti-RBD) titers is limited, particularly in the context of XBB.1.5-adapted vaccination. <h4>Methods</h4> A direct comparison of neutralizing activity, measured as 50% neutralization (NT 50 ), and anti-RBD titers, measured using an ELISA, was conducted using serum samples collected in J...

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Literature Corpus work
89cc3b3e-39e9-58ea-908e-c27ae31bd824
DOI
10.1101/2025.03.13.25323892
Open publication

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Strain-specific anti-RBD IgG antibody titers against the WT, XBB.1.5, JN.1, and KP.3 strains consistently correlate with neutralizing activity following SARS-CoV-2 XBB.1.5-adapted mRNA vaccinationDOI 10.1101/2025.03.13.25323892
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