Article

Reduced TLR3 and TLR9 Expression in Epidermodysplasia Verruciformis: Evidence from a Comparative Skin Study

2025-08-04

Abstract excerpt

Epidermodysplasia verruciformis (EV) is a rare genodermatosis characterized by lifelong β-human papillomavirus (HPV) persistence, extensive flat warts, and increased risk of cutaneous squamous cell carcinoma. While TMC6 and TMC8 mutations are recognized as genetic drivers, innate immune mechanisms contributing to HPV persistence remain incompletely defined. This study investigated Toll-like receptors (TLRs) 3, 4,...

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Literature Corpus work: 444e0f95-f734-53c6-883e-ae8907e43db2
DOI: 10.22541/au.175432530.08457532/v1

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