Article

Myeloablation-associated deletion of ORF4 in a human coronavirus 229E infection

2017-03-03

Abstract excerpt

We describe metagenomic next-generation sequencing (mNGS) of a human coronavirus 229E from a patient with AML and persistent upper respiratory symptoms, who underwent hematopoietic cell transplantation (HCT). mNGS revealed a 548-nucleotide deletion, which comprised the near entirety of the ORF4 gene, and no minor allele variants were detected to suggest a mixed infection. As part of her pre-HCT conditioning regime...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 33727f69-3213-5168-a2db-9d9ee8befc52
DOI: 10.1101/113423

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 11 closest

Myeloablation-associated deletion of ORF4 in a human coronavirus 229E infectionDOI 10.1101/113423Read

Prolonged Shedding of Human Coronavirus in Hematopoietic Cell Transplant Recipients: Risk Factors and Viral Genome EvolutionSemantic proximity Read

Cell-free DNA Profiling Informs Major Complications of Hematopoietic Cell TransplantationSemantic proximity Read

Implementation of a multiplex PCR amplfication system combined with next-generation genome sequencing to decipher the circulation of Human coronavirus 229E lineages in Southern FranceSemantic proximity Read

Integration of an anellovirus genome in the SKNO-1 acute myeloid leukemia cell lineSemantic proximity Read

Transcriptomic profiling and genomic mutational analysis of Human coronavirus (HCoV)-229E -infected human cellsSemantic proximity Read

A plasma-based DNA test for quantification of disease burden in acute myeloid leukemia patients undergoing bone marrow transplantationSemantic proximity Read

Use of whole-genome sequencing in the molecular investigation of care-associated HCoV-OC43 infections in a hematopoietic stem cell transplant unit.Semantic proximity Read

Transcriptomic profiling of human corona virus (HCoV)-229E -infected human cells and genomic mutational analysis of HCoV-229E and SARS-CoV-2Semantic proximity Read

Whole-Genome Approach to Assessing Human Cytomegalovirus Dynamics in Transplant Patients Undergoing Antiviral TherapySemantic proximity Read

Persistent low-level variants in a subset of HCMV genes are highly predictive of poor outcome in immunocompromised patients with cytomegalovirus infectionSemantic proximity Read

Using Whole Genome Sequences to Investigate Adenovirus Outbreaks in a Hematopoietic Stem Cell Transplant UnitSemantic proximity Read