Article

Screening of Conserved Non-Coding Elements with Enhanced Activity of SHOX Gene in PAR1 Region and Its Regulation Mechanism on SHOX Gene

2020-08-14

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Defects in conserved non-coding elements (CNEs) are associated with a large number of genetic diseases. The short-chain homeobox gene (SHOX) is regulated by different CNEs in the upstream and downstream, and these CNEs can act as enhancers as homeopathic regulatory elements. Abnormal CNEs upstream and downstream of the SHOX gene can result in short stature of di...

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Literature Corpus work: 1291111c-d009-5ac5-b01d-22049e74da63
DOI: 10.21203/rs.3.rs-54595/v1

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