Auditory stimuli as a trigger for arrhythmic events differentiate HERG-related (LQTS2) patients from KVLQT1-related patients (LQTS1).

doi:10.1016/s0735-1097(98)00578-6

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Article

Auditory stimuli as a trigger for arrhythmic events differentiate HERG-related (LQTS2) patients from KVLQT1-related patients (LQTS1).

Journal of the American College of Cardiology - 1 Feb 1999

Wilde A A, Jongbloed R J, Doevendans P A, Düren D R, Hauer R N, van Langen I M, van Tintelen J P, Smeets H J, Meyer H, Geelen J L

Abstract excerpt

OBJECTIVE: This study was performed to identify a possible relationship between genotype and phenotype in the congenital familial long QT syndrome (cLQTS). BACKGROUND: The cLQTS, which occurs as an autosomal dominant or recessive trait, is characterized by QT-interval prolongation on the electroc...

Topics

Acoustic Stimulation
Adult
Aged
Aged, 80 and over
Cation Transport Proteins
DNA
DNA Probes
DNA-Binding Proteins
Death, Sudden, Cardiac
Disease Progression
ERG1 Potassium Channel
Electrocardiography
Ether-A-Go-Go Potassium Channels

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Female

Follow-Up Studies

Genotype

Heart Rate

Humans

Source

Open in PubMed

Identifiers

PMID: 9973011
DOI: 10.1016/s0735-1097(98)00578-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9973011-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.