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Article

Auditory stimuli as a trigger for arrhythmic events differentiate HERG-related (LQTS2) patients from KVLQT1-related patients (LQTS1).

Journal of the American College of Cardiology - 1 Feb 1999

Wilde A A, Jongbloed R J, Doevendans P A, Düren D R, Hauer R N, van Langen I M, van Tintelen J P, Smeets H J, Meyer H, Geelen J L

Abstract excerpt

OBJECTIVE: This study was performed to identify a possible relationship between genotype and phenotype in the congenital familial long QT syndrome (cLQTS). BACKGROUND: The cLQTS, which occurs as an autosomal dominant or recessive trait, is characterized by QT-interval prolongation on the electrocardiogram and torsade de pointes arrhythmias, which may give rise to recurrent syncope or sudden cardiac death....

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PMID: 9973011
DOI: 10.1016/s0735-1097(98)00578-6

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