Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prolongation of life in an experimental model of aging in Drosophila melanogaster.

Neurochemical research - 1 Feb 1999

Jordens R G, Berry M D, Gillott C, Boulton A A

Abstract excerpt

(R)-Deprenyl, the archetypical monoamine oxidase-B inhibitor, has been shown to increase life-span in a number of species. Although many theories for this effect have been suggested, for example, an increase in superoxide dismutase (SOD) activity, the mechanism of action has yet to be elucidated. To investigate this phenomenon, we have examined the effects of (R)-deprenyl, and some aliphatic propargylamines, in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Drosophila melanogaster
Share to Galactose

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Longevity

Share to Mutation

Share to Reactive Oxygen Species

Share to Sucrose

Share to Superoxide Dismutase

Source

Identifiers

PMID: 9972869
DOI: 10.1023/a:1022510004220

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prolongation of life in an experimental model of aging in Drosophila melanogaster.PMID 9972869Read ↗

Drosophila melanogaster as a model system in the study of pharmacological interventions in agingSemantic proximity Read ↗

Protocols to Study Aging in Drosophila.Semantic proximity Read ↗

Genetic alteration of normal aging processes is responsible for extended longevity in Drosophila.Semantic proximity Read ↗

Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants.Semantic proximity Read ↗

Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of Age-Associated Aging Genes in <i>Drosophila melanogaster</i>Semantic proximity Read ↗

Drosophila as a model system for studying lifespan and neuroprotective activities of plant-derived compoundsSemantic proximity Read ↗

Regulation of Drosophila life-span: effect of genetic background, sex, mating and social status.Semantic proximity Read ↗

Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster.Semantic proximity Read ↗

Life History Traits of an Extended Longevity Phenotype of Drosophila melanogaster.Semantic proximity Read ↗

Extension of life span and stress resistance of Drosophila melanogaster by long-term supplementation with melatoninSemantic proximity Read ↗

Resveratrol and Lifespan in Model OrganismsSemantic proximity Read ↗

Life Span and Locomotor Activity Modification by Glucose and Polyphenols in Drosophila melanogaster Chronically Exposed to Oxidative Stress-stimuli: Implications in Parkinson’s DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.