Article
An alpha-tectorin gene defect causes a newly identified autosomal recessive form of sensorineural pre-lingual non-syndromic deafness, DFNB21.
Human molecular genetics - 1 Mar 1999
Mustapha M, Weil D, Chardenoux S, Elias S, El-Zir E, Beckmann J S, Loiselet J, Petit C
Abstract excerpt
In our efforts to identify new loci responsible for non-syndromic autosomal recessive forms of deafness, DFNB loci, we have pursued the analysis of large consanguineous affected families living in geographically isolated areas. Here, we report on the study of a Lebanese family comprising nine mem...
Topics
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- DNA Mutational Analysis
- DNA Primers
- Deafness
- Extracellular Matrix Proteins
- Female
- GPI-Linked Proteins
- Genes, Dominant
- Genes, Recessive
- Genetic Linkage
- Heterozygote
- Humans
- Lebanon