Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Peutz-Jeghers syndrome: molecular analysis of a three-generation kindred with a novel defect in the serine threonine kinase gene STK11.

The American journal of gastroenterology - 1 Jan 1999

Trojan J, Brieger A, Raedle J, Roth W K, Zeuzem S

Abstract excerpt

The Peutz-Jeghers syndrome, phenotypically characterized by mucocutaneous pigmentation and hamartomatous polyposis, is an autosomal dominant disease with variable expression and incomplete penetrance. Moreover, affected patients are at increased risk for gastrointestinal and other malignancies. Recently, a mutated gene encoding abnormal forms of the novel serine threonine kinase STK11 has been identified as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Exons
Share to Frameshift Mutation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Mutation

Share to Pedigree

Share to Polymerase Chain Reaction

Share to Protein Serine-Threonine Kinases

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 9934767
DOI: 10.1111/j.1572-0241.1999.00810.x

Genes

STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Peutz-Jeghers syndrome: molecular analysis of a three-generation kindred with a novel defect in the serine threonine kinase gene STK11.PMID 9934767Read ↗

A novel de novo mutation in the serine-threonine kinase STK11 gene in a Korean patient with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A De Novo mutation of STK11 gene in a Chinese patient with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A 23-Nucleotide Deletion in STK11 Gene Causes Peutz-Jeghers Syndrome and Malignancy in a Chinese Patient Without a Positive Family History.Semantic proximity Read ↗

A novel mutation in STK11 gene is associated with Peutz-Jeghers Syndrome in Indian patients.Semantic proximity Read ↗

Novel mutations in the STK11 gene in Thai patients with Peutz-Jeghers syndrome.Semantic proximity Read ↗

Three novel mutations of STK11 gene in Chinese patients with Peutz-Jeghers syndrome.Semantic proximity Read ↗

Analysis of STK11 gene variant in five Chinese patients with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A novel missense mutation of the STK11 gene in a Chinese family with Peutz-Jeghers syndrome.Semantic proximity Read ↗

Two cases of somatic STK11 mosaicism in Danish patients with Peutz-Jeghers syndrome.Semantic proximity Read ↗

A novel mutation in STK11 gene is associated with Peutz-Jeghers syndrome in Chinese patients.Semantic proximity Read ↗

Lung cancer as a predominant feature in a patient with Peutz-Jeghers syndrome: Case report.Semantic proximity Read ↗

De novo germline mutation in the serine–threonine kinase STK11/LKB1 gene associated with Peutz–Jeghers syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.