Article
Disorders of sexual differentiation.
Endocrinology and metabolism clinics of North America - 1 Dec 1998
Warne G L, Zajac J D
Abstract excerpt
An infant born with ambiguous genitalia requires an accurate and prompt diagnosis so that a management plan can be formulated. This article discusses the signaling cascade of genes that controls sexual differentiation. Clinical disorders involving sex reversal or ambiguous genitalia are discussed in relation to the genes regulating sexual development. An approach to the treatment of these disorders is outlined.
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