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Article

Mutations in the gene for the common gamma chain (gammac) in X-linked severe combined immunodeficiency.

Human genetics - 1 Dec 1998

Fugmann S D, Müller S, Friedrich W, Bartram C R, Schwarz K

Abstract excerpt

X-linked severe combined immunodeficiency (XSCID) constitutes a disorder of the immune system caused by mutations in the gene encoding the common gamma chain (gammac), a subunit of the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors, which are necessary for lymphocyte development and function. In this study the IL2RG gene of 31 patients with severe combined immunodeficiency (SCID) was examined by nonradioactive...

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Source

Identifiers

PMID: 9921912
DOI: 10.1007/pl00008710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in the gene for the common gamma chain (gammac) in X-linked severe combined immunodeficiency.PMID 9921912Read ↗

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