Evidence of phenotypic alteration as a cause of systolic dysfunction in the failing heart.

doi:10.1016/s0733-8651(05)70044-8

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Article

Evidence of phenotypic alteration as a cause of systolic dysfunction in the failing heart.

Cardiology clinics - 1 Nov 1998

Feldman A M, Kubota T, Li Y Y, Wagner D, Combes A, McTiernan C

Abstract excerpt

This article describes the phenotype of dilated cardiomyopathy in humans and describes parallel studies in experimental models that support or refute the relevance of these changes to the development of the heart failure phenotype.

Topics

Adenylyl Cyclases
Animals
Calcium
Cardiomyopathy, Dilated
GTP-Binding Proteins
Heart
Homeostasis
Humans
Phenotype
Receptors, Adrenergic
Signal Transduction
Systole

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