Article
Fine-structure mapping of the hereditary inclusion body myopathy locus.
Genomics - 1 Jan 1999
Eisenberg I, Thiel C, Levi T, Tiram E, Argov Z, Sadeh M, Jackson C L, Thierfelder L, Mitrani-Rosenbaum S
Abstract excerpt
The gene responsible for a recessive form of hereditary inclusion body myopathy (HIBM) has previously been mapped to a 10-cM interval on chromosome 9p1-q1. We report the results of further mapping studies using two-point linkage analyses and linkage disequilibrium analyses with 20 HIBM families....
Topics
- Chromosomes, Human, Pair 9
- Female
- Humans
- Jews
- Linkage Disequilibrium
- Male
- Mutation
- Myositis, Inclusion Body
- Pedigree
- Physical Chromosome Mapping
- Polymorphism, Genetic
- Tropomyosin