Article
Fine-structure mapping of the hereditary inclusion body myopathy locus.
Genomics - 1 Jan 1999
Eisenberg I, Thiel C, Levi T, Tiram E, Argov Z, Sadeh M, Jackson C L, Thierfelder L, Mitrani-Rosenbaum S
Abstract excerpt
The gene responsible for a recessive form of hereditary inclusion body myopathy (HIBM) has previously been mapped to a 10-cM interval on chromosome 9p1-q1. We report the results of further mapping studies using two-point linkage analyses and linkage disequilibrium analyses with 20 HIBM families. We demonstrate that the HIBM gene (HGMW-approved symbol IBM2) lies between loci D9S1791 and D9S50, which are about 1 Mb...
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