Article
Familial clustering of rheumatoid arthritis with other autoimmune diseases.
Human genetics - 1 Oct 1998
Lin J P, Cash J M, Doyle S Z, Peden S, Kanik K, Amos C I, Bale S J, Wilder R L
Abstract excerpt
Previous studies have shown that rheumatoid arthritis aggregates within families. However, no formal genetic analysis of rheumatoid arthritis in pedigrees together with other autoimmune diseases has been reported. We hypothesized that there are genetic factors in common in rheumatoid arthritis and other autoimmune diseases. Results of odds-ratio regression and complex segregation analysis in a sample of 43...
Read the complete abstract on PubMedTopics
- Adult
- Arthritis, Rheumatoid
- Autoimmune Diseases
- Family
- Female
- Genotype
- Humans
- Middle Aged
- Models, Genetic
- Odds Ratio
