Identification of a hereditary pancreatitis mutation in four West Virginia families.

doi:10.1203/00006450-199812000-00017

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Article

Identification of a hereditary pancreatitis mutation in four West Virginia families.

Pediatric research - 1 Dec 1998

Elitsur Y, Chertow B C, Jewell R D, Finver S N, Primerano D A

Abstract excerpt

Hereditary pancreatitis (HP) is the second most common cause of chronic childhood pancreatitis in the United States. Mutations in the cationic trypsinogen gene on chromosome 7 are known to cause HP. We identified four families in West Virginia with symptoms consistent with HP. To determine whethe...

Topics

Child
Chromosomes, Human, Pair 7
Female
Genetic Linkage
Genetic Markers
Haplotypes
Humans
Male
Mutation
Pancreatitis
Pedigree
Polymorphism, Restriction Fragment Length
Trypsinogen
West Virginia

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