Article
[Primary hypercholesterolemia: mechanisms of its development in man].
Ukrainskii biokhimicheskii zhurnal (1978) - 1 Jan 2000
Chernyshov V A
Abstract excerpt
The review is devoted to hypercholesterolemia which is one of the leading risk factors for IHD. By its origin it can be primary and secondary. Three major mechanisms of primary hypercholesterolemia in humans are discussed. They are: low activity of LDL receptors, reduced affinity of LAL for recep...
Topics
- Apolipoproteins B
- Apolipoproteins E
- Genetic Therapy
- Humans
- Hyperlipoproteinemia Type II
- Mutation
- Receptors, LDL
- Risk Factors
