Description of a new DRB1*11 allele (DRB1*1132).

doi:10.1111/j.1399-0039.1998.tb03064.x

Article

Description of a new DRB111 allele (DRB11132).

Tissue antigens - 1 Oct 1998

Loiseau P, Loste M N, Lepage V, Schaeffer V, Lethielleux P, Tilanus M, van Der Zwan A W, Dubel L, Nigou M, Johanet C, Charron D

Abstract excerpt

We describe a new DRB1*11 allele which is similar to DRB1*11011 except at codon 74, where a GCG is changed for a GTG leading to an alanine/valine substitution. This new allele was carried by a Caucasian patient suffering from rheumatoid arthritis and by her healthy daughter. The motif at codon 74...

Topics

Alleles
Arthritis, Rheumatoid
Base Sequence
Codon
Female
HLA-DR Antigens
HLA-DRB1 Chains
Haplotypes
Humans
Molecular Sequence Data
Point Mutation
Polymorphism, Restriction Fragment Length

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