Article
Description of a new DRB1*11 allele (DRB1*1132).
Tissue antigens - 1 Oct 1998
Loiseau P, Loste M N, Lepage V, Schaeffer V, Lethielleux P, Tilanus M, van Der Zwan A W, Dubel L, Nigou M, Johanet C, Charron D
Abstract excerpt
We describe a new DRB1*11 allele which is similar to DRB1*11011 except at codon 74, where a GCG is changed for a GTG leading to an alanine/valine substitution. This new allele was carried by a Caucasian patient suffering from rheumatoid arthritis and by her healthy daughter. The motif at codon 74 of the new DRB1*11 is not found in any other known DRB alleles, nor among the published DQA1, DQB1, DPA1 or DPB1...
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