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Article

Development of a scheme for genotyping Helicobacter pylori based on allelic variation in urease subunit genes.

Journal of clinical microbiology - 1 Dec 1998

Owen R J, Slater E R, Xerry J, Peters T M, Teare E L, Grant A

Abstract excerpt

Helicobacter pylori urease subunit genes in 383 isolates from 10 countries were investigated by PCR-restriction fragment length polymorphism (HaeIII) analysis. Eighty-two different ureAB profiles were documented by reference to known sequences. Variation among 51% of strains was accounted for by 10 predominant patterns, which provided a unique framework for categorizing isolates with geographically diverse origins.

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Identifiers

PMID: 9817904
DOI: 10.1128/JCM.36.12.3710-3712.1998
PMCID: PMC105271

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