Are Dp71 and Dp140 brain dystrophin isoforms related to cognitive impairment in Duchenne muscular dystrophy?

doi:10.1002/(sici)1096-8628(19981102)80:1<32::aid-ajmg6>3.0.co;2-y

Back to search

Article

Are Dp71 and Dp140 brain dystrophin isoforms related to cognitive impairment in Duchenne muscular dystrophy?

American journal of medical genetics - 30 Oct 1998

Moizard M P, Billard C, Toutain A, Berret F, Marmin N, Moraine C

Abstract excerpt

Molecular study and neuropsychological analysis were performed concurrently on 49 patients with Duchenne muscular dystrophy (DMD) in order to find a molecular explanation for the cognitive impairment observed in most DMD patients. Complete analysis of the dystrophin gene was performed to define t...

Topics

Adolescent
Base Sequence
Brain
Child
Cognition Disorders
DNA Primers
Dystrophin
Gene Rearrangement
Humans
Muscular Dystrophies
Mutation
Neuropsychological Tests

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.