A second family with nonsyndromic sensorineural hearing loss linked to Xp21.2: refinement of the DFN4 locus within DMD.

doi:10.1006/geno.1998.5538

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Article

A second family with nonsyndromic sensorineural hearing loss linked to Xp21.2: refinement of the DFN4 locus within DMD.

Genomics - 1 Nov 1998

Pfister M H, Apaydin F, Turan O, Bereketoglu M, Bylgen V, Braendle U, Zenner H P, Lalwani A K

Abstract excerpt

X-linked inherited hearing impairment is a group of heterogeneous disorders accounting for less than 2% of hereditary hearing loss. DFN4, a sex-linked hearing impairment associated with profound sensorineural hearing loss, has been previously mapped to Xp21.2, a region containing the DMD locus. W...

Topics

Chromosome Mapping
Dystrophin
Female
Genetic Linkage
Hearing Loss, Sensorineural
Humans
Lod Score
Male
Muscular Dystrophies
Pedigree
Phenotype
X Chromosome

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