Article
Association of a G994-->T missense mutation in the plasma platelet-activating factor acetylhydrolase gene with genetic susceptibility to nonfamilial dilated cardiomyopathy in Japanese.
Circulation - 3 Nov 1998
Ichihara S, Yamada Y, Yokota M
Abstract excerpt
BACKGROUND: Although several genes or genetic loci that are responsible for or confer susceptibility to familial dilated cardiomyopathy (DCM) have been identified, genetic defects that underlie nonfamilial DCM remain to be characterized. Mice lacking manganese superoxide dismutase exhibit DCM, su...
Topics
- 1-Alkyl-2-acetylglycerophosphocholine Esterase
- Adult
- Aged
- Base Sequence
- Cardiomyopathy, Dilated
- Echocardiography
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Japan
- Male
- Middle Aged
- Mutation, Missense
- Phospholipases A
- Reference Values