Article
[Phenotypic characterization of erythromycin resistance in strains of the genus Streptococcus isolated from clinical specimens].
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia - 1 Sept 1998
Limia A, Jiménez M L, Delgado T, Sánchez I, López S, López-Brea M
Abstract excerpt
There are presently two recognized mechanisms of resistance to macrolide antibiotics in species of the genus Streptococcus: target modification and efflux. Target modification occurs in the ribosomes through the production of a ribosomal methylase codified for the erm genes and it is phenotypically known as MLSB resistance. Expression of MLSB resistance can be inducible or constitutive. Active efflux has been...
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