The myosin ATPase inhibitor 2,3-butanedione-2-monoxime (BDM) inhibits tip growth and cytokinesis in the fission yeast, Schizosaccharomyces pombe.

doi:10.1002/(SICI)1097-0169(1998)41:2<117::AID-CM3>3.0.CO;2-B

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Article

The myosin ATPase inhibitor 2,3-butanedione-2-monoxime (BDM) inhibits tip growth and cytokinesis in the fission yeast, Schizosaccharomyces pombe.

Cell motility and the cytoskeleton - 1 Jan 1998

May K M, Wheatley S P, Amin V, Hyams J S

Abstract excerpt

The growth of fission yeast cultures was reversibly inhibited by exposure to the myosin-ATPase inhibitor 2,3-butanedione-2-monoxime (BDM). Wild-type cells treated with 20 mM BDM for approximately two generation times were smaller than untreated controls and had a septation index approximately twi...

Topics

Actins
Cell Division
Cell Polarity
Diacetyl
Genes, cdc
Indoles
Microscopy, Fluorescence
Microtubules
Mutation
Myosins
Schizosaccharomyces
Spindle Apparatus
Temperature

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