Article
Neonatal hyperbilirubinemia and mutation of the bilirubin uridine diphosphate-glucuronosyltransferase gene: a common missense mutation among Japanese, Koreans and Chinese.
Biochemistry and molecular biology international - 1 Sept 1998
Akaba K, Kimura T, Sasaki A, Tanabe S, Ikegami T, Hashimoto M, Umeda H, Yoshida H, Umetsu K, Chiba H, Yuasa I, Hayasaka K
Abstract excerpt
We analyzed the bilirubin uridine diphosphate-glucuronosyltransferase (B-UGT) gene in 42 Japanese newborns with hyperbilirubinemia and determined that 21 infants were heterozygous while 3 was homozygous for Gly71Arg. Allele frequency of Gly71Arg was 0.32 in newborns with hyperbilirubinemia, which...
Topics
- Alleles
- Asian People
- China
- Gene Frequency
- Glucuronosyltransferase
- Heterozygote
- Homozygote
- Humans
- Hyperbilirubinemia
- Infant, Newborn
- Japan
- Korea
- Mutation, Missense
- Polymerase Chain Reaction