Article
Relationship between conversion of localized juvenile periodontitis-susceptible children from health to disease and Actinobacillus actinomycetemcomitans leukotoxin promoter structure.
Journal of periodontology - 1 Sept 1998
Bueno L C, Mayer M P, DiRienzo J M
Abstract excerpt
The periodontal pathogen Actinobacillus actinomycetemcomitans produces a leukotoxin that is considered a primary virulence factor in localized juvenile periodontitis (LJP). Select strains of the bacterium contain a 530-bp deletion in the promoter region of the leukotoxin gene operon which results...
Topics
- Adolescent
- Aggregatibacter actinomycetemcomitans
- Aggressive Periodontitis
- Bacterial Toxins
- Base Pairing
- Child
- Clone Cells
- Cytotoxins
- DNA, Bacterial
- Disease Progression
- Disease Susceptibility
- Exotoxins
- Female
- Gene Deletion
- Gene Expression Regulation, Bacterial